The mean BMI was 31.3. The mean glycated hemoglobin level at baseline was 9.4 percent. Hypertension was present in 72 percent of sufferers, and 40 percent had already got a cardiovascular event. A brief history of microvascular complications was reported in 62 percent of the patients. At baseline, 52 percent of the individuals were receiving insulin. The mean baseline blood circulation pressure was 132/76 mm Hg in both groups. After 6 years, for individuals who had been in follow-up still, the mean blood pressure was 125/69 mm Hg in the standard-therapy group and 127/68 mm Hg in the intensive-therapy group. In both groups, mean lipid amounts improved through the study, and levels of low-density lipoprotein cholesterol decreased to 80 mg per deciliter .As was the case in Buffalo, needles had been changed with each use of the insulin pens, the Olean medical center said. The risk of infection remained, however, because stored insulin in the pen cartridge could have become contaminated by a back flow of blood with each use. ‘We are very aware that as the risk of infection from insulin pen re-use is incredibly small, cross-contamination from an insulin pen can be done,’ Finan said.