AVEO submits tivozanib NDA with FDA for treatment of advanced renal cell carcinoma AVEO Oncology and Astellas Pharma Inc ed pills . today announced that AVEO offers submitted a New Drug Application to the U.S. Meals and Medication Administration seeking authorization for tivozanib in sufferers with advanced renal cell carcinoma . Tivozanib is designed to focus on the vascular endothelial development factor pathway, a clinically validated target in RCC and various other solid tumors. In TIVO-1, tivozanib demonstrated a statistically significant improvement in progression-free of charge survival versus sorafenib, an authorized targeted agent, and a favorable tolerability profile.
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