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Study 2: This study focuses on the use of quetiapine to treat bipolar patients with both hypomania and depression.Who is eligible: Volunteers for this study must be experiencing both hypomania – a distinct period of elevated mood, lasting for at least four days – and depressive symptoms.What is required: Participants will be carefully evaluated and assigned at random either quetiapine or placebo over a period of 8 weeks to receive rx pharmacy . They will be supervised by a psychiatrist and be compensated for the time and travel costs.

The researchers will continue to volunteer for an ongoing study of the use of ziprasidone for bipolar patients with weight gain treat treat a common side effect of some medications. In a 12-week period, participants will be evaluated carefully and undertaken with ziprasidone , and efforts to reduce or discontinue medication increase in weight.

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