In individuals with MG.

Alexion announces that FDA grants ODD to Soliris for Myasthenia Gravis treatment Alexion Pharmaceuticals today announced that the U.S. In individuals with MG, uncontrolled complement activation due to antibodies fond of the neuromuscular junction can ultimately result in profound and debilitating weakness of varied muscle groups through the entire body . ‘Individuals with MG develop debilitating muscle weakness, impairing their ability to walk, speak obviously, swallow and, in some full cases, to breathe normally, which could result in a life-threatening myasthenic crisis,’ stated Martin Mackay, Ph.D., Executive Vice President, Global Head of R&D at Alexion.

In the journal Nucleic Acids Research, researchers from the National Institute on Alcoholic beverages Misuse and Alcoholism and the National Institute of Requirements and Technology statement that polyamines – natural substances essential for cell growth – react with acetaldehyde to result in a number of reactions that harm DNA, an event that can lead to the formation of cancer. ‘We’ve long suspected acetaldehyde’s part in the carcinogenicity of alcohol beverage consumption, but this study gives us essential fresh clues about its involvement,’ says Ting-Kai Li, M.D., director of the NIAAA, portion of the National Institutes of Health.