The company did not adequately present that those differences didn’t cause these items to improve different questions of public health, he said. Speaking at the news headlines briefing, David Ashley, director of the Office of Science at FDA’s Middle for Tobacco Products, stated that harmful elements in the brand new products included increased amounts of the chemicals toluene and formaldehyde, and dyes. There have been also high degrees of menthol and fresh ingredients that could affect toxicity, Ashley stated.. FDA Bans Sale of New R.J. Reynolds Cigarettes: – TUESDAY, Sept. 15, 2015 – – The U.S. Drug and Meals Administration has ordered the R.J. Reynolds Tobacco Co. To stop selling four new cigarette brands because they violate provisions of this year’s 2009 tobacco control regulation. The agency established that the smokes are substantially different from existing Reynolds tobacco items in the marketplace and need a full agency examine before they can be marketed.3.8 percent, P<0.001) included bleeding and peptic ulceration, along with other problems in the upper and lower gastrointestinal tracts .7 percent vs. 3.0 percent, P<0.7 percent vs. 0.4 percent, P=0.0 percent vs. 6.6 percent, P<0.001) was distributed across a variety of sites and types of disease .5 percent vs. 1.9 percent, P<0.001) was distributed across a number of sites . Searchable tabulations of all the significant adverse events , along with all the adverse reactions that were not considered to be serious, are provided in Supplementary Appendix 2, offered by NEJM.org.