The most common unwanted effects of Keytruda included fatigue, decreased appetite, shortness of breath or impaired breathing, and cough. The medication also offers the potential to trigger severe immune system-related side effects involving the lungs, colon, hormone-generating glands, nervous system, and also bloodstream and rash vessel swelling, the FDA said. Pregnant or breast-feeding women shouldn’t take the drug because it may harm the fetus or baby, the agency noted. Earlier this full 12 months, the FDA approved the Bristol-Myers Squibb drug Opdivo – – which also targets the PD-1/PD-L1 pathway – – to take care of squamous non-little cell lung cancer.Although the new global estimates are slightly less than the previously released estimates, the actual amount of people living with HIV has not decreased; the epidemic continues to grow predicated on revised 2001 estimates rather.D.: Transitional Chaos or Enduring Damage? The EHR and the Disruption of Medicine A decade ago, a primary care physician We admired appeared to come undone. His performance had derived not from rushing between sufferers but from knowing them so well that his charting was effortless and fast. But all of a sudden he became distracted, losing his grasp on the details of his sufferers’ lives.