Adding common epilepsy drug to morphine can lead to better discomfort control, say IU researchers Adding a common epilepsy medication to a morphine routine can lead to better discomfort control with fewer side effects. Moreover, the dosage can be reduced by the combination of the opioid would have to be effective, according to a group of pain experts at Indiana University More information here . The result could bring significant alleviation to numerous patients with neuropathic pain, a difficult-to-deal with condition often sensed in the arms and legs and connected with nerve tissue damage.
These data suggest the functional variation of pika leptin.. Adaptive useful evolution of leptin in cold-adaptive pika family Researchers in the Northwest Institute of Plateau Biology, Chinese Academy of Sciences have put forward the viewpoint for the very first time that adaptive functional evolution may occur in the leptin protein of the pika family, a typical cold-adaptive mammal. They speculated that the cold, than hypoxia rather, may be the main environmental aspect that drives the adaptive evolution of pika leptin. In the January 23 issue of PLoS ONE This study is published. The low hypoxia and temperature are the two most remarkable climatic characteristics of the Plateau. During development, pikas have become highly hypoxic – and low temperature-tolerant mammals with markedly high resting metabolic prices, non-shivering thermogenesis, and a high ratio of oxygen utilization to handle the hypoxic and cold plateau environment.