Part 1 is normally a dose-escalation research of dalantercept in conjunction with axitinib to evaluate the safety and tolerability of the combination as second series treatment. Part 2 is an open-label, randomized study to determine whether treatment with dalantercept in combination with axitinib prolongs progression free of charge survival in comparison to treatment with axitinib only. For additional information on this clinical trial, please check out clinicaltrials.gov, identifier NCT01727336.. Acceleron commences dalantercept stage 2 study in metastatic renal cell carcinoma Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for tumor and orphan illnesses, announced the initiation of a phase 2 study of dalantercept, a novel angiogenesis inhibitor that targets the activin receptor-like kinase 1 pathway.Health experts want to determine if the full cases are linked. Both diseases can develop from pneumonia. ‘Given the parents’ issues and our worries, we experienced that out of abundance of caution we’d keep universities closed for the next two days,’ said Dr. David Gifford, state public wellness director. Furthermore, the Catholic Diocese of Providence shut eight schools in three communities, with a mixed 2,600 learners, as a precaution. No full instances of meningitis or encephalitis have already been reported among the students, stated diocese spokesman Michael Guilfoyle.