Kaiser Health News, an unbiased news service editorially, is a scheduled plan of the Kaiser Family Foundation, a nonpartisan healthcare policy research corporation unaffiliated with Kaiser Permanente.. ARCA biopharma receives technique patent for treatment with bucindolol predicated on genetic targeting ARCA biopharma, Inc. , a biopharmaceutical firm developing genetically targeted treatments for cardiovascular diseases, today announced that the U.S. Patent and Trademark Office has released a patent on methods for determining whether to manage or prescribe bucindolol to a patient based on whether the patient has a particular genotype – homozygous for the arginine 389 polymorphism in the beta-1 adrenergic receptor.Study drug dose adjustment during the study had not been allowed. All concomitant medications were kept constant throughout the scholarly study, including diuretic brokers, RAAS inhibitors, and antidiabetic therapies. No dietary limitations were imposed; sufferers were instructed to continue their usual diet without the specified alterations. Research stopping rules are included in the protocol. An institutional review board or independent ethics committee at each participating institution accepted the study, which was conducted in accordance with the Good Scientific Practice guidelines and the provisions of the Declaration of Helsinki.