Related StoriesStudy discovers high prevalence of dehydration in the elderly living in UK care homesLiposomal sizing and the Coulter theory: an interview with Professor Melvin E. KlegermanMayo Clinic's Florida campus awarded NIH grant to recognize vascular risk factors in ageing and dementiaProfessor of Cellular Neuroscience, Zafar Bashir and his team have got demonstrated how electrical stimulation of the prefrontal cortex leads to the release of acetylcholine from synaptic terminals and the subsequent weakening of synaptic connections between neurons. When acetylcholine is normally released it binds to particular receptors and starts a molecular cascade which triggers physiological alterations in how prefrontal cortical neurons are ‘wired’ collectively. The findings suggest that the persistent weakening of synaptic connections between neurons induced by the endogenous launch of acetylcholine in the prefrontal cortex may underlie the formation of new associative thoughts.The team observed that the very best time to go for a post-food walk was after the evening meal. The exaggerated rise in blood sugar after this meal-frequently the largest of the day-often lasts well in to the night and morning hours which was curbed significantly when the participants started to walk on the home treadmill, DiPietro said. Most people eat a big afternoon or evening meal and take a nap or watch tv then. That's the worst thing you can do, DiPietro said. Let the food digest a little bit and then obtain out and move, she says. A walk timed to check out the big dinner is specially important because this study suggests high post-dinner blood sugar is a strong determinant of excessive 24-hour sugar levels, DiPietro said.